In a previous study on Revelation 12 I mentioned the woman that John saw in the heavens, and showed that she represented Israel, giving birth to Jesus, according to the flesh (cf. Hebrews 7:14; Romans 1:3; Revelation 5:5; 22:16). Continuing in this study, John saw another wonder (G4952 – semeion) or sign in the heavens. It was a dragon, which in the context of the sign of the woman being Virgo, this second sign must be Draco the dragon constellation (Revelation 12:3) that appears in the sign Sagittarius.
Although some of the signs have been corrupted, given different names with different stories behind them, it was God who originally set them in the heavens and called them out by name (Psalm 147:4). He had a purpose in doing so. Otherwise, why would he do such a thing? Does he number the trees of the earth or the earth’s rocks and call them by name? There isn’t a record of him doing that, but, knowing that God has a purpose for doing the things he does, we are able to conclude that there must be some meaning behind the stars in the heavens. The Scriptures seem to say the Lord singled out the constellations and named them, so we could honor him by seeking out why he had done such a thing (Proverbs 25:2).
We need to keep in mind that from the very beginning, God set the lights in the heavens not only to give physical light to the earth, but to be for signs in their seasons (Genesis 1:14-18), not for the purpose of predicting personal matters in one’s life (Isaiah 47:13), but for the purpose of revealing the spiritual work of God (Psalm 19:1; 97:6). Paul, speaking of the Gospel that is written in the heavens, claimed it went to all people throughout the world (Romans 10:13-21). Nevertheless, as I said above, these things were corrupted by those who didn’t want to have God in their knowledge. The Lord named all the stars (Psalm 147:4), even the constellations (Job 9:9; 38:31), and these things speak of the work of God (Psalm 102:25). Although they knew the Lord at one time (Romans 1:18-20), men corrupted that knowledge by changing the work of God into the fashion of men, birds, beasts and creeping things (Romans 1:21-23, 28).
How could Enoch have known how to walk with God, since there is no record of a preacher showing him how to do it (Genesis 5:22)? How could Noah have walked with God (Genesis 6:9) and become a preacher of righteousness (2Peter 2;5), since, except for commanding him to build an ark, it isn’t recorded that God told him how to walk with him or how to preach the things Noah preached? Nevertheless, the names of the stars and the constellations that are in the heavens preach the Gospel throughout the world, and John in Revelation 12 points to two of those signs, the one (Virgo) predicting the birth of the Messiah, who was to rule from heaven, and the other (Draco) pointing to the evil works of those who tried to prevent that from happening.
John described what he saw, saying it was a red dragon, having seven heads and seven crowns upon his heads. Actually, the constellation, Draco, has only one head, but taken together with all the constellations pointing to him, he has seven heads. There are also seven stars in Draco’s head and tongue, which proceeds out of its mouth. Therefore, since we know the dragon is Satan or the Enemy, the Devil or Slanderer (Revelation 12:9), we may look for his other heads elsewhere in the Zodiac to discover their meaning there.
The sign, Draco, appears only in the northern hemisphere, and is circumpolar, which means it never sets; it is always visible in the northern sky. Its brightest star, Thuban, meaning subtle in Hebrew, used to be the polar star some 4600 years ago, but due to the wobble of the earth’s axis (precession of the equinox), it has moved out of the true northerly direction. So, in the days when the great pyramid was supposed to have been built, Thuban, which is in the tail of Draco, was the polar star. Therefore, one could say that Satan, the “god of this world” (2Corinthians 4:4, cf. Revelation 12:9), was the guiding light, exerting a subtle influence upon our world.
One of the minor constellations in the sign, Virgo, is Coma, meaning the desired (of the nations – cf. Haggai 2:7). The constellation is that of a woman holding a child. In the heavens the head of Draco is positioned to strike at the child, soon after he was born (Revelation 12:4). So, although these things are written in the stars for us to understand, they depict things that were to occur on earth (e.g. Matthew 2:1-18). They prophesied of the times of Jesus and his Apostles.
 Besides Draco we find Satan in the constellations: Serpens, Cerberus (three headed monster), Cetus, the sea monster (known as Leviathan in the Bible: Job 41:1; Psalm 74:14; Isaiah 27:1), and Hydra, the monstrous serpent who winds its way through four constellations (or 1/3 of the stars of heaven, see Revelation 12:4), five beasts, seven heads. What is interesting is they all get slain or are bound by a strong man in the heavens, who is Christ.
 This is an ancient name of the constellation, which on modern maps is Coma Berenicae, the wig of Berenice, wife of Ptolemy III, an obvious corruption of the original ancient constellation. See E.W. Bullinger, The Witness of the Stars, pages 34 & 35.